Semi Prep Guard Column Cartridge, RP C12, 10um, 100A. 10mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Information:

Cogent RP C12 Semi-Preparative Guard Column Cartridges are packed with the same unique stationary phase used in Cogent RP C12 semi-preparative columns. The adamantane-based bonded phase features a rigid, diamond-like carbon structure attached to high-purity silica with complete double endcapping. This distinctive chemistry provides excellent performance for complex mixtures, rapid equilibration between runs, and compatibility with 100% aqueous mobile phases while helping maintain the selectivity characteristics of RP C12 semi-preparative columns.

68012-SP-PG1 contains five guard column cartridges packed with 10 µm RP C12 material featuring a 100 Å pore size in 10 mm ID x 10 mm length stainless steel hardware. Designed specifically for use with 10 mm ID semi-preparative HPLC columns, these guard cartridges help intercept particulates, strongly retained contaminants, and sample matrix components before they reach the main column. The matching stationary phase chemistry preserves chromatographic selectivity while protecting valuable semi-preparative columns from contamination and premature fouling.

Used in semi-preparative purification, fraction collection, process development, and method scale-up workflows, these guard cartridges help preserve column efficiency, improve reproducibility, and reduce replacement costs. The stainless steel cartridge construction and stainless steel frits provide excellent durability for routine purification operations while maintaining the chromatographic performance of RP C12 semi-preparative columns.

Key Benefits

  • Packed with Cogent RP C12 stationary phase

  • Unique adamantane-based bonded phase

  • Fully double endcapped chemistry

  • High-purity silica support

  • Compatible with 100% aqueous mobile phases

  • Protects semi-preparative HPLC columns from contaminants

  • Helps maintain column efficiency and reproducibility

  • Extends semi-preparative column service life

  • Stainless steel cartridge construction

  • Supplied as a convenient 5-pack

Typical Applications

  • Semi-preparative HPLC purification

  • Fraction collection

  • Compound isolation

  • Pharmaceutical research

  • Synthetic chemistry

  • Natural product purification

  • Process development

  • Method scale-up

  • Production support purification

  • Semi-preparative column protection

Specifications

  • Product Type: Semi-Preparative Guard Column Cartridges

  • Stationary Phase: RP C12

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Adamantane-Based C12 Ligand

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Cartridge Dimensions: 10 mm ID x 10 mm

  • Hardware Material: Stainless Steel

  • Frit Material: Stainless Steel

  • Quantity: 5/PK

  • Brand: Cogent

Guard Column Holder Requirement

Additional Resources

Special Order Item Information

Important Notes

  • Compatible with Cogent RP C12 semi-preparative HPLC columns

  • Compatible with 100% aqueous mobile phases

  • Designed to intercept particulates and contaminants before they reach the main column

  • Maintains RP C12 selectivity characteristics during purification

  • Recommended for routine purification and scale-up workflows

  • Replace guard cartridges as needed based on sample cleanliness and application requirements

  • Special Order Item


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